DOM4SEHAT Consortium
Deep Ocean Mission · Ministry of Earth Sciences · Government of India
Deep Ocean Mission · Ministry of Earth Sciences · Government of India
Advancing Genomic Science & Marine Biotechnology to discover high-value bioresources for Global Human Health and Industrial Innovation.
Key milestones from India's Deep Ocean Bioresources exploration programme
Search through millions of annotated genomic records from the Indian Peninsula.
Harnessing marine organisms for therapeutic and industrial breakthroughs through innovative extraction platforms.
Multi-OMIC characterization of biodiversity to discover novel marine resources with translational potential.
Coordinated by BRIC-ILS Bhubaneswar, this mission unites top research institutes across India (ICGEB, NCCS, IBSD, and more) to develop commercially relevant knowledge and socially beneficial technologies from our vast ocean heritage.
Exploring the Marine Ecosystems for Novel Bioresources with Human Health and Industrial Significance
Exploring the Marine Ecosystems for Novel Bioresources with Human Health and Industrial Significance — is a Deep Ocean Mission (DOM), Ministry of Earth Sciences initiative led by BRIC–Institute of Life Sciences (ILS), Bhubaneswar, in collaboration with NCCS Pune, ICGEB New Delhi, IBSD Imphal, IIT Bhubaneswar, KIIT, and IISER Berhampur, with support from NIOT, NCCR, CMLRE, and regional universities.
The project aims to explore, characterize, and harness marine microbial biodiversity across Odisha’s coastal ecosystems, including Bhitarkanika, Chilika, and associated estuaries, as well as the wider deep ocean. Through an integrated multi-omics approach encompassing metagenomics, metabarcoding, whole-genome sequencing, metabolomics, and advanced bioinformatics, DOM4SEHAT seeks to build a comprehensive marine genomic and metabolite knowledge base and uncover the functional and biotechnological potential of marine microorganisms.
The programme encompasses marine biodiversity exploration, next-generation sequencing and AI/ML-driven bioinformatics, high-throughput bioprospecting of therapeutically significant natural products such as anticancer, antiviral, and immunomodulatory compounds, and the discovery of industrially valuable enzymes, nutraceuticals, probiotics, and other marine bioresources, supported by a dedicated Marine Bioinformatics Facility.
Metagenomics, metabarcoding, whole-genome sequencing (WGS), and metabolomics building a unified genomic and metabolite knowledge base.
High-throughput bioprospecting for novel anticancer, antiviral, and immunomodulatory bioactive compounds from deep ocean and coastal strains.
Discovery and characterization of industrial enzymes, biocatalysts, functional nutraceuticals, probiotics, and high-value marine bio-innovations.
Supported by a dedicated Marine Bioinformatics Facility deploying next-gen AI/ML tools for predictive annotation and genome mining.
By connecting marine biodiversity with biotechnology and translational research, DOM4SEHAT aims to advance the discovery of novel drug candidates, industrial biocatalysts, nutraceuticals, and other high-value products, while establishing integrated marine multi-omics data infrastructure, strengthening India’s marine biotechnology capabilities, supporting the Blue Economy, and contributing to the national vision of Viksit Bharat @2047.
