DEEP OCEAN EXPLORATION • BIG PICTURE OVERVIEW

DOM4SEHAT Research Overview

An integrated multi-tiered exploration of the Bay of Bengal marine bioresources. From deep ocean sampling expeditions to whole-genome sequencing, environmental metagenomics, and industrial bioprospecting.

5
Transects
20 Stations →
84
Metagenomics
66.69M Reads →
1,076
Strains Isolated
Pure Cultures →
506
WGS
Sequenced →
161
Representative Species
Taxa Catalog →
962
Metabolites Identified
21 Strains →
1. Metagenomic Community Diversity 2. Genomic Overview 3. Proteomics Overview 4. Metabolomics & Bioprospecting

1. Metagenomic Community Diversity

Taxonomic abundance profile derived from 66,687,893 sequencing reads across 84 metagenomic samples and 5 coastal transects.

Open Interactive Diversity Explorer
Domain Distribution (66.69M Reads)
Top 8 Phyla Abundance (%)
84
Metagenomes Sequenced
66.69M
High-Quality Reads
5
Coastal Transects
20
Sampling Depth Stations

2. Genomic Overview

View 450 Isolate Drill-Downs →
506
Total assembled genome
69
Representative Genera
157
Representative Species
35
BGC class
Genus Taxonomic Composition
Biosynthetic Gene Cluster (BGC) Diversity
Industrial Enzyme & Bioprospecting Clustered Heatmap
Scale:
Click any genus row to explore its WGS isolates in the Strain catalog Drag to zoom matrix; double-click to reset view.

3. Proteomics Overview

Translational protein targets, UniProt mappings, and functional enzymatic receptor profiles from deep-sea isolates.

Search Protein Targets →
100
Proteome of Bacterial Isolates
15
Industrially Important Enzyme Classes
4000+
Uncharacterized Protein
5800+
Antimicrobial Peptides
Mass Spectrometry & Target Annotation LC-MS/MS • UniProt • Antimicrobial Profiling
Deep Ocean Proteomics & Target Characterization

The DOM4SEHAT proteomics workflow connects high-resolution mass spectrometry (LC-HRMS) with annotated microbial proteomes, antimicrobial peptide prediction pipelines, and functional enzyme profiling across deep-sea marine bacterial isolates.

  • Bacterial Isolates Proteome: 100 complete isolate proteomic profiles cataloged.
  • Industrial Biocatalysts: 15 distinct enzyme classes with biotechnological application potential.
  • Novel & Uncharacterized Proteins: 4,000+ uncharacterized deep-sea proteins for dark matter exploration.
  • Antimicrobial Peptides: 5,800+ predicted AMP candidates screened for therapeutic and antagonistic activity.
Marine Bioprospecting & Protein Repositories Search Protein Targets →

4. Metabolomics and Bioprospecting Overview

Metabolomics Library →
84
Total Extracts
962
Metabolites Identified
84.2%
Lipinski Pass
459
Active Metabolites
Distribution of metabolites across Extraction Phase & Solvent Polarity
Distribution of metabolites across different biosynthetic classes
Reported bioactivity of active metabolites